Fig. 6From: miR-18a-5p derived from mesenchymal stem cells-extracellular vesicles inhibits ovarian cancer cell proliferation, migration, invasion, and chemotherapy resistanceNACC1 overexpression reversed the inhibition of hMSC-EVs on OC cell proliferation, migration and invasion. NACC1 overexpression was accomplished in EVs-treated CAOV3/ES2 cells. A WB was used to detect the expression of NACC1; B MTT assay was adopted to assess cell viability; C, D Transwell assays were performed to detect OC cell migration and invasion. Cell experiments were replicated 3 times. Data were showed as mean ± SD. One-way ANOVA was performed for comparisons between groups and Tukey's multiple comparisons test was adopted for the post hoc test. ***P < 0.001Back to article page