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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Identification of mutation patterns and circulating tumour DNA-derived prognostic markers in advanced breast cancer patients

Fig. 1

CtDNA mutation profile of Chinese ABC patients and the distribution of variations among different IHC subtypes. A Somatic mutation landscape of 141 Chinese ABC patients. The bar chart above the heatmap shows the ctDNA fractions of all baseline samples in the cohort. In the heatmap, the top bars depict the number of mutations a patient carried and the bars below denote different IHC subtypes. Each column represents one patient, and each row represents one gene. The text on the left represents gene names. The values on the right represent the mutation rates of these genes. Distributions of (B) the top 10 somatic mutations and (C) the top 10 CNVs among the three IHC subtypes. ABC, advanced breast cancer; ctDNA, circulating tumour DNA; IHC, immunohistochemistry; CNVs, copy number variations

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