Table 2 Sclerostin expression alteration in alveolar bone during orthodontic tooth movement
From: Sclerostin is a promising therapeutic target for oral inflammation and regenerative dentistry
Animal | Force (g) | Time (days) | Sclerostin level | Detection method | Refs. | |
|---|---|---|---|---|---|---|
Tension side | Compression side | |||||
Mouse | 10 | 4 | ↓ | ↑ | Confocal fluorescence imaging | [42] |
Rat | 20 | 1 | ↓ | ↑ | Immunohistochemistry | [48] |
7 | ↓ |  →  | ||||
28 | ↓ | ↓ | ||||
Mouse | 10 | 1 | ↓ | ↓ | Immunofluorescence | [46] |
5 |  →  | ↑ | ||||
10 |  →  |  →  | ||||
Mouse | 10 | 14 | ↑a | ↑a | Immunohistochemistry | [47] |