Sclerostin is a promising therapeutic target for oral inflammation and regenerative dentistry

Table 1 The expression of sclerostin in oral tissues and cells

Cell/tissue	Species	Detection methods	Refs.
Gingival crevicular fluid	Human	ELISA/qPCR	[32,33,34,35,36]
Gingiva	Human	ELISA/qPCR	[37, 38]
Periodontal ligament cell	Human	Western Blot/qPCR Immunohistochemistry Immunofluorescent staining	[39,40,41]
Periodontal ligament cell	Mouse	Confocal microscopy	[42]
Osteocytes in alveolar bone	Human	Immunohistochemistry	[39, 43]
	Mouse	LacZ staining/qPCR Immunohistochemistry Immunofluorescent staining	[39, 42, 44,45,46,47]
	Rat	Immunohistochemistry	[48,49,50,51]
Odontoblast	Human	Immunohistochemistry	[52, 53]
Odontoblast	Mouse	Immunohistochemistry	[45, 54]
Odontoblast-like cell	Human	Western blot/qPCR	[52, 55]
Odontoblast-like cell	Mouse	Immunohistochemistry	[56]
Dental pulp stem cell	Human	Western blot/qPCR	[53, 55, 57]
Dental pulp stem cell	Mouse	qPCR	[56]
Cementocyte	Human	Immunohistochemistry qPCR	[39, 58]
Cementocyte	Mouse	Immunohistochemistry LacZ staining	[39, 44, 59, 60]

ELISA enzyme-linked immunosorbent assay; qPCR quantitative real-time polymerase chain reaction

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