Fig. 4From: Sclerostin is a promising therapeutic target for oral inflammation and regenerative dentistryCurrent understanding about the role of sclerostin in periodontitis. A In periodontitis condition, the expression of sclerostin and RANKL is increased while the expression of periostin is decreased. B Sclerostin participates in periodontitis development by regulating periodontal ligament morphology and alveolar bone metabolism. RANKL receptor activator of nuclear factor-κB ligandBack to article page