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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Sclerostin is a promising therapeutic target for oral inflammation and regenerative dentistry

Fig. 4

Current understanding about the role of sclerostin in periodontitis. A In periodontitis condition, the expression of sclerostin and RANKL is increased while the expression of periostin is decreased. B Sclerostin participates in periodontitis development by regulating periodontal ligament morphology and alveolar bone metabolism. RANKL receptor activator of nuclear factor-κB ligand

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