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Table 3 Risk factors analysis

From: Causal relationship between physical activity, leisure sedentary behaviors and COVID-19 risk: a Mendelian randomization study

Exposure Outcomes IVW Heterogeneity MR-Egger method
Causal effect (95% CI) P Q value P Intercept P
Accelerometer assessed physical activity Body mass index − 0.01 (− 0.05,0.025) 0.56 16.91   − 0.019  
Accelerometer assessed physical activity Total cholesterol − 0.82 (− 2.52,0.88) mmol/L 0.34 4.43 0.49 0.23 0.84
Accelerometer assessed physical activity Triglycerides − 0.008 (− 0.27, 0.01) mmol/L 0.42 43.52  < 0.001 − 0.008 0.50
Accelerometer assessed physical activity Type 2 diabetes 1.04 (0.93, 1.16) 0.49 2.35 0.31 − 0.1 0.39
Accelerometer assessed physical activity Fasting insulin 1.01 (0.99, 1.04)   3.99   − 0.014  
Accelerometer assessed physical activity Former versus current smoker 0.97 (0.86, 1.08) 0.56 10.13 0.04 0.13 0.19
Accelerometer assessed physical activity Cigarettes smoked per day 1.12 (0.77, 1.61) 0.56 0.80 0.94 0.08 0.80
Television watching Body mass index 0.25 (0.15, 0.35) 1.53 × 10–7* 148.43  < 0.001 − 0.0003 0.95
Television watching Total cholesterol 0.66 (− 5.84, 7.18) mmol/L 0.84 131.1 0.001 0.23 0.40
Television watching Triglycerides 0.26 (0.17, 0.35) mmol/L 1.22 × 10–8 * 844.7  < 0.001 0.003 0.30
Television watching Type 2 diabetes 1.82 (1.25, 2.65) 1.79 × 10–3 * 95.54 0.0014 − 0.007 0.71
Television watching Fasting insulin 0.15 (0.09, 0.21) pmol/L 2.52 × 10–6 * 85.87 0.02 0.004 0.23
Television watching Former versus current smoker 0.69 (0.53, 0.90) 0.007 * 77.57 0.22 − 0.006 0.62
Television watching Cigarettes smoked per day 0.73 (− 0.82, 2.28) 0.36 95.85 0.02 0.04 0.63
  1. *P < 0.05