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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Hsa_circ_0000497 and hsa_circ_0000918 contributed to peritoneal metastasis of ovarian cancer via ascites

Fig. 2

Transcriptomics profiling identifies biological processes of EMT in ovarian cancer via the peritoneal circulation. a PCA score plot of the mRNA expression data of primary tumor lesions (T), ascites tumor cells (ASC) and metastatic lesions (M), The convex whole of the sample distributions in PCA. PCA: principal component analysis. Each point represents a dimensional reduction spectrum. All data were separated by sample type, and the automatic combination can better reflect the nature of different tissue cells. b Heatmap showing the enrichment levels (ssGSEA scores) of epithelial signatures and mesenchymal signature in mRNA expression of T, ASC, and M. ssGSEA: single sample gene-set enrichment analysis. c Heatmap for expression of genes from the EMT signature in T, ASC, and M. Red represents high expression levels; Green represents low expression levels; Each row represents a circRNA; Each column represents the expression profile of a sample

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