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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Inhibition of NOS1 promotes the interferon response of melanoma cells

Fig. 5

NOS1-inhibition increase the clinical effect of melanoma. ASTAT1, TLR3, GBP3 and GBP5 significantly negatively correlated with NOS1. \(R{}^2>0.25\). B The graph of NPLA-treatment group (IFN\(\upalpha \)-NPLA vs. NPLA) and control group (IFN\(\upalpha \) vs. control) showed 30 unique NOS1-IFN related genes. C Left panel: The heatmap of 14 NOS1-IFN related genes in 471 clinical samples. Right panel: The overall survival time of the group of high-expression NOS1-IFN related genes was significantly longer than that of the low expression group. (***\(\hbox {p} < 0.001\)). D The remission of the high-expression NOS1-IFN related genes group was significantly longer than that of the low expression group. (**\(\hbox {p} < 0.01\))

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