Fig. 4
From: Inhibition of NOS1 promotes the interferon response of melanoma cells
NOS1 deletion inhibits lung metastasis of melanoma. A HE staining shows the diameter of lung nodule was small in NOS1-KO group than WT (***\(\hbox {p} < 0.001\)). B Immunohistochemistry shows the intensity of Ki67 were decreased and CD3 increased in NOS1-KO than WT group. The proliferation index of Ki-67 was investigated through IHC in xenograft tumors. Scale bar: \(50 \; \upmu \hbox {m}\)