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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification

Fig. 8

Overexpression of ISG15 promote migration and invasion ability of PCa cells. A, B Relative mRNA expression of ISG15 in PC-3 and 22RV-1 transfected with plasmids ISG15, NC, sh-ISG15, and sh-NC. C Overexpression of ISG15 promoted migration of PC-3 and 22RV-1. D Overexpression and knockdown of ISG15 promoted and inhibited, respectively, invasion ability of PC-3 and 22RV-1. **P < 0.01, ***P < 0.001,****P < 0.0001

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