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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification

Fig. 7

Expression of ISG15 and ZFP36 is increased and decreased in PCa respectively and is correlated with hypoxia. A The expression of ISG15 and ZFP36 increased and decreased respectively in PCa than in paracancerous tissues. B, C The expression of ISG15 and ZFP36 were significantly higher and lower respectively in PC-3, 22RV-1, LNCaP than in RWPE-1 at transcription level and protein level. D–K The expression level of ISG15 and ZFP36 in PC-3,22RV-1 and LNCaP was increased and decreased by the hypoxia at transcription level and protein level. **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. RWPE-1 and 0 h

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Journal of Translational Medicine

ISSN: 1479-5876

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