Fig. 1From: CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signalingCYP2E1 level is downregulated in HCC and the low expression of CYP2E1 is negatively related to malignant clinicopathologic features of HCC patients. A CYP2E1 mRNA levels in adjacent nontumor tissues and HCC tissues were analyzed by RT-qPCR (n = 88). B CYP2E1 protein levels in paired adjacent nontumor (N) and tumor (T) tissues measured by western blot assay. C Representative images of IHC staining for CYP2E1 in paired adjacent nontumor and tumor tissues. Bar = 50 μm. D–H The effect of tumor size (D), vascular invasion (E), degree of differentiation (F), smoking (H), and alcohol consumption (I) on CYP2E1 mRNA level in tumor tissues. G Kaplan–Meier curves for overall survival in HCC patients with variable CYP2E1 expressionBack to article page