Table 3. Identification of hub genes by PPI network
Up-regulated miRNAs | Down-regulated miRNAs | ||
|---|---|---|---|
Gene | Degree | Gene | Degree |
MAPK1 | 34 | AKT1 | 76 |
PTEN | 27 | VEGFA | 68 |
SYK | 25 | MAPK1 | 65 |
TAF1 | 23 | EGFR | 63 |
CDKN1A | 22 | MYC | 59 |
POLR2E | 21 | IL6 | 57 |
PRKCA | 21 | BCL2 | 52 |
CDK4 | 19 | ACTB | 44 |
SH3GL1 | 19 | SMAD4 | 43 |
DNAJC10 | 18 | ESR1 | 42 |