Fig. 5

Identification of two hub genes and prediction of their relationship with immune cell content and experimental validation of their expression in the DLBCL TMA cohort. A Venn diagram analysis showed that the overlap of WGCNA analysis and LASSO model led to two hub genes being identified: PLTP and PHKA1. B Prediction of correlations between hub genes and immune cell content. C Prediction of correlations between hub genes and immune checkpoints. D Differences in PLTP expression between reactive hyperplasia tissues and DLBCL tissues with mIHC (p value by Wilcoxon rank-sum test). E Differences in PHKA1 expression between reactive hyperplasia tissues and DLBCL tissues with mIHC (p value by Wilcoxon rank-sum test)