Mechanism and clinical value of exosomes and exosomal contents in regulating solid tumor radiosensitivity

Table 2 Exosomes as diagnostic, prognostic or predictive biomarker in solid tumor

Exosomes/Exosomal contents	Cancer types	Specimen origin	Biomarker function	References
Exosome circMYC	NPC	Serum	Differentiate radioresistant patients from patients with radiosensitive NPC	[38]
Exosome miR-339-5p	ESCC	Serum	Predict radiotherapeutic response	[46]
Exosome miR-96	NSCLC	Plasma	Diagnostic and prognostic marker of radioresistant NSCLC	[50]
Exosome miR-378	NSCLC	Serum	Predict radiotherapeutic response	[51]
Exosome miR-29a-3p miR-150-5p	NSCLC	Serum	Predict radiotherapeutic response; radiation-related	[52]
Exosome HSP70	NSCLC	Plasma	Predict radiotherapeutic response	[55]
Exosome miR-663a	CRC	Plasma	Predict radiotherapeutic response	[67]
Exosome miR-574-3p	Glioblastoma	Serum	Predict radiotherapeutic response	[85]
Exosome miR-379-5p miR-654-3p	Prostate cancer	Serum	Predict radiotherapeutic response	[91]
Exosome proteome	Breast cancer	Body fluids	Differentiate radiation-resistant tumors	[99]

ISSN: 1479-5876