Fig. 2

Elevated expression of LINC01564 predicts poor clinical outcomes in GC patients. The mRNA expression of LINC01564 was stratified into high or low expression. The association of LINC01564 expression with the progression of GC was analyzed using the Kaplan–Meier survival curves (A) and GEPIA (B); similarly, the association of POU2F1 expression with the progression of GC was analyzed using the Kaplan–Meier survival curves (C) and GEPIA (D). Using data from TCGA database, we analyzed the expression of POU2F1 and lncRNA LINC01564 in patients with or without GC metastasis (E). Moreover, we analyzed the expression of POU2F1 and LINC01564 using the data from GSE26253 dataset (F). As indicated by the results from GSE26253 dataset, high expression of LINC01564 and POU2F1 are associated to poor OS and recurrence free survival (RFS) (G). The RNA levels of LINC01564 and POU2F1 in normal adjacent tissues (n = 10), primary GC tissues (n = 10), and metastasis GC tissues (n = 10) were analyzed using qPCR (H) and Western blot (I). Significant differences are indicated by *p < 0.05, **p < 0.01 and ***p < 0.001