Fig. 2

ANGPT2 upregulation during HG exposure. A Representative immunoblot of ANGPT2, STX4 and DNM2. B Densitometric analysis of ANGPT2 immunoblot signals (n ≥ 3). ^*P < 0.05 vs. NG (normal glucose). C Densitometric analysis of STX4 immunoblot signals (n ≥ 3). No statistical significance vs. NG. D Densitometric analysis of DNM2 immunoblot signals (n ≥ 3). No statistical significance vs. NG. E Representative immunohistochemical (IHC) staining of ANGPT2 in diabetic kidney. F Statistical data of IHC staining of ANGPT2 (n ≥ 5). ^**P < 0.01 vs. Control