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Fig.1 | Journal of Translational Medicine

Fig.1

From: Transcriptomic profiling of pemphigus lesion infiltrating mononuclear cells reveals a distinct local immune microenvironment and novel lncRNA regulators

Fig.1

Gene expression and correlation analysis. The volcano plot illustrates DEGs (including mRNA and lncRNA) between healthy control and pemphigus after analysis of a mRNA of SIMC. b lncRNA of SIMC. c mRNA of PBMC.d lncRNA of PBMC. The y-axis indicates the statistical significance expressed as the log10 of the p-values and the x-axis shows the rate of expression change between experimental groups in log2 base (log2 Fold change), p Value cutoff = 0.05, LogFC cut 1 or – 1. e Authentication of 17 common DEGs in SIMC and PBMC datasets trough Venn diagrams. f Co-expression analysis of common DEGs in SIMC and PBMC. Pairwise correlations based on expression levels were computed for each pair of genes in the matrix shown above. Only genes with a Pearson coefficients value > 0.75 and p value < 0.05 are shown. Positive correlations are indicated in red shades and negative ones in blue shades. DEGs, differentially expressed genes. Nonsig, not statistically significant

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