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Table 1 Clinical characteristics of patients included in the study

From: circMAP3K4 regulates insulin resistance in trophoblast cells during gestational diabetes mellitus by modulating the miR-6795-5p/PTPN1 axis

Parameter

GDM

(n = 42)

NGT

(n = 42)

P value

Maternal age (years)

33.36 ± 4.85

31.48 ± 4.71

0.075

Pre-pregnancy BMI (kg/m2)

24.41 ± 4.77

25.98 ± 5.26

0.156

Weight gain during pregnancy (kg)

12.10 ± 2.72

9.52 ± 2.98

0.000***

Gravidity history

2.38 ± 1.27

1.95 ± 1.31

0.131

Parity history

0.40 ± 0.54

0.36 ± 0.48

0.673

Gestational age (days)

268.10 ± 10.19

272.74 ± 6.63

0.016*

OGTT at diagnosis of GDM or at 24 ~ 28 weeks of gestation

   

 0 min glucose (mmol/L)

5.28 ± 0.56

4.52 ± 0.22

0.000***

 60 min glucose (mmol/L)

10.10 ± 1.79

7.15 ± 1.24

0.000***

 120 min glucose (mmol/L)

8.68 ± 1.67

6.28 ± 0.93

0.000***

AUC (mmol·L−1·h−1)

12.56 ± 1.53

17.02 ± 2.37

0.000***

FPG at delivery (mmol/L)

4.79 ± 0.68

4.24 ± 0.49

0.000***

HbA1c at delivery (%)

5.61 ± 0.56

5.32 ± 0.31

0.006**

Baby's sex (female) (n[n%])

22 (52.38)

20 (47.62)

0.663

Birth weight (g)

3445.48 ± 483.68

3374.40 ± 486.82

0.504

Placental weight (g)

628.36 ± 103.55

613.95 ± 123.42

0.023

Apgar score (1 min)

9.88 ± 0.55

9.90 ± 0.37

0.817

  1. GDM: gestational diabetes mellitus; BMI: body mass index; OGTT: oral glucose tolerance test; AUC: area under curve; FPG: fasting blood glucose; HbA1c: glycosylated hemoglobin
  2. Data are expressed as mean ± standard deviation or n (n%), *P < 0.05, **P < 0.01, ***P < 0.001