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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: circMAP3K4 regulates insulin resistance in trophoblast cells during gestational diabetes mellitus by modulating the miR-6795-5p/PTPN1 axis

Fig. 6

miR-6795-5p binds to PTPN1. A The predicted binding sites of PTPN1 on miR-6795-5p and mutant binding sites. B The dual-luciferase reporter assay was used to confirm the interactions between PTPN1 and miR-6795-5p. C Representative immunofluorescence of PTPN1 in the GDM and NGT groups. D PTPN1 mRNA expression in the GDM (n = 42) and NGT (n = 42) groups as determined by qPCR. E PTPN1 expression in HTR-8/SVneo cells in the different groups was determined by qPCR. The cell experiment was repeated three times. *P < 0.05, **P < 0.01, ***P < 0.001, ns: no significant difference

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