Fig. 5

circMAP3K4 silencing partially restored insulin signaling in trophoblasts through miR-6795-5p. A The protein expression levels of IRS1, p-IRS1, Akt, and p-Akt were determined by western blotting, the representative images were displayed. B A glucose uptake assay was performed to determine the glucose uptake abilities of HTR-8/SVneo cells. C CCK8 assay was performed to determine the cell growth of HTR-8/SVneo cells. The cell experiment was repeated three times. *P < 0.05, **P < 0.01, ***P < 0.001, ns: no significant difference