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Table 2 Frequencies of IgG, IgA and IgE responses in sera of COVID-19 patients collected > 14 DPS, %

From: Early and strong antibody responses to SARS-CoV-2 predict disease severity in COVID-19 patients

Antigen Mild, % Moderate, % Severe, % Total, %
IgG IgA IgE IgG IgA IgE IgG IgA IgE IgG IgA IgE
Full-lenght proteins or subunits
 SFL3 94.7 16.7 66.7 100 38.5 92.3 100 54.5 90 97.3 30.1 79.7
 SFL 97.4 25 12.1 100 42.3 50 100 54.5 60 98.7 35.6 33.3
 SRBD 92.1 22.2 0 100 42.3 3.85 100 63.6 10 96 35.6 2.9
 S1sub 89.5 22.2 0 100 42.3 34.6 100 63.6 20 94.7 35.6 15.9
 S2sub 100 25 3.03 100 42.3 19.2 100 54.5 20 100 35.6 11.6
 NFL 94.7 19.4 66.7 100 46.2 96.2 100 45.5 100 97.3 32.9 82.6
 MFL 84.2 13.9 0 100 30.8 23.1 100 45.5 0 92 24.7 8.7
Predicted epitopes or protein fragments
 S1 5.26 0 0 7.69 0 0 27.3 0 0 9.33 0 0
 S2 31.6 0 0 26.9 0 0 72.7 0 0 36 0 0
 S3 26.3 0 0 26.9 0 0 54.5 0 0 30.7 0 0
 S4 5.26 0 0 15.4 0 0 36.4 0 0 13.3 0 0
 S5 34.2 0 0 23.1 0 0 36.4 0 0 30.7 0 0
 S6 13.2 0 0 15.4 0 3.85 0 0 0 12 0 1.45
 S7 42.1 2.78 15.2 69.2 0 34.6 90.9 0 30 58.7 1.37 24.6
 S8 13.2 0 0 15.4 3.85 0 18.2 0 0 14.7 1.37 0
 S9 28.9 0 0 26.9 0 0 45.5 0 0 30.7 0 0
 S10 15.8 0 0 15.4 0 0 18.2 0 0 16 0 0
 S11 0 0 0 7.69 0 7.69 18.2 0 0 5.33 0 2.9
 M1 18.4 0 0 38.5 0 0 54.5 0 0 30.7 0 0
 N1 28.9 0 0 30.8 3.85 0 54.5 0 0 33.3 1.37 0
 N2 42.1 0 0 53.8 0 0 63.6 0 0 49.3 0 0
 NSP1 36.8 0 0 15.4 0 0 36.4 0 0 29.3 0 0
 NSP2 7.89 0 0 11.5 0 0 27.3 0 0 12 0 0
 NSP3 2.63 0 ND 11.5 0 ND 9.09 0 ND 6.67 0 ND
 NSP4 2.63 0 ND 3.85 0 ND 0 0 ND 2.67 0 ND
 NSP5 31.6 0 ND 34.6 0 ND 45.5 0 ND 34.7 0 ND
 ORF3b 2.63 0 ND 3.85 0 ND 18.2 0 ND 5.33 0 ND
 ORF8 7.89 0 ND 7.69 0 ND 18.2 0 ND 9.33 0 ND
 ORF8_1 0 0 ND 0 0 ND 0 0 ND 0 0 ND
 ORF8_2 5.26 0 ND 15.4 0 ND 27.3 0 ND 12 0 ND