Table 1 Clinical characteristics of patients with familial hypercholesterolemia and their relatives
From: SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia
Characteristic | Patients with FH | Relatives without FH | p value |
|---|---|---|---|
No | 30 | 30 | |
Age, mean ± SD, y | 45.0 ± 15.8 | 42.5 ± 16.5 | 0.588 |
Male, No. (%) | 18 (60.0%) | 16 (53.3%) | 0.602 |
BMI, mean ± SD | 23.3 ± 3.4 | 24.7 ± 2.8 | 0.836 |
Hypertension | 10 (33.3%) | 12 (40.0%) | 0.592 |
Diabetes mellitus | 3 (10.0%) | 5 (16.7%) | 0.448 |
CAD | 16 (53.3%) | – | – |
Current smoking | 8 (26.7%) | 7 (23.3%) | 0.766 |
Lipid-lowering therapy | 28 (93.3%) | – | – |
TC, mmol/L | 9.23 ± 2.17 | 5.35 ± 3.15 | < 0.001 |
LDL-C, mmol/L | 7.76 ± 1.09 | 3.40 ± 2.71 | < 0.001 |
TG, mmol/L | 1.79 ± 1.53 | 1.63 ± 1.00 | 0.655 |
HDL-C, mmol/L | 1.25 ± 1.10 | 1.34 ± 0.42 | 0.673 |