Table 1 Patient characteristcs of the resectable (i) and recurrent (ii) cohort
From: FOXO transcriptional activity is associated with response to chemoradiation in EAC
| Â | Resectable cohort (i) | Recurrent cohort (ii) | ||
|---|---|---|---|---|
n = 236 | 100% | n = 66 | 100% | |
Mean age at dianosis | 57.6 | (36–81) | 64.7 | (40–85) |
Sex | ||||
 Male | 200 | 84.7 | 51 | 77.3 |
 Female | 36 | 15.3 | 15 | 22.7 |
Location | ||||
 Proximal | 1 | 0.4 | 0 | 0.0 |
 Mid | 1 | 0.4 | 3 | 4.5 |
 Distal | 58 | 24.6 | 41 | 62.1 |
 GEJ | 176 | 74.6 | 22 | 33.3 |
T-stage | ||||
 1 | 5 | 2.1 | 3 | 4.5 |
 2 | 35 | 14.8 | 5 | 7.6 |
 3 | 192 | 81.4 | 57 | 86.4 |
 4 | 4 | 1.7 | 1 | 1.5 |
N-stage | ||||
 0 | 75 | 31.8 | 16 | 24.2 |
 1 | 140 | 59.3 | 41 | 62.1 |
 2 | 1 | 0.4 | 7 | 10.6 |
 3 | 20 | 8.5 | 2 | 3.0 |
Treatment | ||||
 nCRT | 172 | 72.9 | 15 | 22.7 |
 nCRT + P | 27 | 11.4 | 2 | 3.0 |
 CRT + HT | 0 | 0.0 | 1 | 1.5 |
 CT | 0 | 0.0 | 1 | 1.5 |
 Surgery only | 37 | 15.7 | 47 | 71.2 |
Mandard grade | ||||
 1 | 26 | 11.0 | 0 | 0.0 |
 2 | 38 | 16.1 | 1 | 1.5 |
 3 | 77 | 32.6 | 10 | 15.2 |
 4 | 40 | 16.9 | 6 | 9.1 |
 5 | 18 | 7.6 | 1 | 1.5 |
 NA | 37 | 15.7 | 48 | 72.7 |
Recurrence | 128 | 54.2 | 66 | 100.0 |
Alive | 75 | 31.8 | 5 | 7.6 |