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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: IL-32 promotes the occurrence of atopic dermatitis by activating the JAK1/microRNA-155 axis

Fig. 3

IL-32 promotes JAK1 expression and activates its downstream signaling pathway in AD. A The expression levels of JAK1 and Bcl-2 in HaCaT cell lines were detected by RT-qPCR. B The protein levels of JAK1, p-JAK1, p-STAT1/3 and STAT1/3 in HaCaT cell lines were detected by Western blot analysis. C The expression levels of JAK1 and Bcl-2 in mouse skin tissues were detected by RT-qPCR (n = 10). D The protein levels of JAK1, p-JAK1, p-STAT1/3 and STAT1/3 in mouse skin tissues were detected by Western blot analysis (n = 10). E Immunohistochemical detection of JAK1, p-JAK1, p-STAT1/3 and STAT1/3 in mouse skin tissues (50 μm). * p < 0.05 vs. control/WT. Cell experiment was repeated for three times

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