Fig. 3

Imaging features of lesions in patients with CVST and animal models. a The T2WI, DWI, and ADC maps are normal in the healthy control. b An area with slightly high signal can be observed in the occipital lobe on T2WI (white arrow), presenting as a low signal area on DWI (red arrow) and a high signal area on ADC (yellow arrow), in patients with CVST. c Images from the first and seventh days after modelling showing no obvious abnormalities in the sham group. d Image from the model group showing a high-signal area on the right side near the SSS on T2WI (white arrows) and DWI (red arrows) maps and a low signal area on ADC map (yellow arrows) on the first day. The image from the seventh day shows some scattered low-density fields on T2WI (white arrows) and DWI (red arrows) maps and a high signal area on ADC map (yellow arrows) at the original oedemic area, indicating the possibility of venous haemorrhage. e Brain oedema volume quantified based on T2WI in animal models. f ADC quantification for model rats. Values are expressed as mean standard deviation. n.s., P > 0.05, *P < 0.05. CVST: cerebral venous sinus thrombosis; T2WI: T2-weighted imaging; SSS: superior sagittal sinus; DWI: diffusion-weighted imaging; ADC: apparent diffusion coefficient