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Table 2 Univariate and multivariate Cox regression models of TPI1 expression in BRCA patients

From: TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5

Variables

Univariate Cox regression

Multivariate Cox regression

HR

95% CI

P

HR

95% CI

P

DFS

 Age (years)

  ≤ 40 vs. > 40

1.157

0.717–1.868

0.551

–

–

–

 TPI1 expression

  High vs. low

1.500

1.041–2.162

0.029*

1.461

1.009–2.114

0.045*

 Tumor size (cm)

  ≤ 2 vs. 2–5 vs > 5

2.116

1.543–2.901

0.000***

1.826

1.333–2.501

0.000***

 Lymph node status

  N0 + N1 vs. N2 + N3

3.774

2.644–5.388

0.000***

3.186

2.207–4.601

0.000***

 Grade

  G1 vs. G2 and G3

2.506

0.924–6.802

0.071

–

–

–

  1. DFS disease-free survival, HR hazard ratio, CI confidence interval