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Table 1 Relationship of TPI1 expression with clinicopathologic features in 362 BRCA patients

From: TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5

Variables

Number of Patients

P (χ2)

TPI1low expression

TPI1high expression

Age (years)

0.516

 ≤ 40

27

37

 

 > 40

139

159

 

Tumor size (cm)

0.059

 ≤ 2

58

92

 

 2–5

100

94

 

 > 5

8

10

 

Lymph node status

0.504

 Negative

88

97

 

 Positive

78

99

 

Clinical stages

0.002**

 I

29

58

 

 II

96

78

 

 III

41

60

 

Grade

0.185

 G1

8

14

 

 G2

118

148

 

 G3

11

6

 

ER

0.596

 Negative

57

58

 

 Positive

92

106

 

PR

0.838

 Negative

33

35

 

 Positive

115

129

 

HER2

0.517

 Negative

118

125

 

 Positive

30

38

 

KI67

0.323

 Negative

23

19

 

 Positive

122

140

 

P53

0.048*

 Negative

93

120

 

 Positive

51

40

 
  1. TPI1, scored > 7, was defined as high expression; ≤ 7, represented low expression. χ2 test was used for comparing groups with low and high TPI1 expression. n = 362
  2. BRCA breast cancer
  3. *p < 0.05 was considered statistically significant
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Journal of Translational Medicine

ISSN: 1479-5876

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