XGBoost-based and tumor-immune characterized gene signature for the prediction of metastatic status in breast cancer

Table 2 The correlation between the selective gene signature and different types of immune cells

Cell type	Cell markers	Tumor		Normal
Cell type	Cell markers	Cor	P	Cor	P
B cell	CD19\|CD38\|BLNK	0.25	***	0.41	***
Naïve T cell	CCR7\|LEF1\|TCF7\|SELL	0.43	*******	0.4	*******
Effector T cell	CX3CR1\|FGFBP2\|FCGR3A	0.3	*******	0.0015	0.99
Resident memory T cell	CD69\|ITGAE\|CXCR6\|MYADM	0.44	*******	0.52	*******
Th1-like	CXCL13\|HAVCR2\|IFNG\|CXCR3\|BHLHE40\|CD4	0.27	***	0.23	**
Treg	FOXP3\|CCR8\|IL2RA	0.24	***	0.19	*
T cell exhaustion	PDCD1\|CTLA4	0.26	***	0.32	*******
Macrophage	CD68\|CD11b	0.25	***	0.041	0.66
TAM	HLA-G\|CD80\|CD86	0.21	***	0.18	0.055
Monocyte	CD14\|CD16A	0.12	***	-0.083	0.38
NK	XCL1\|KIR3DL1\|CD7	0.22	***	0.092	0.33
Neutrophil	CD15\|MPO	0.25	***	0.091	0.34
DC	CD1C\|CD141	0.39	*******	0.19	*
Fibroblasts	AIFM2\|S100A4	0.06	0.03	− 0.26	***

Bold value represents condition which correlation coefficient > 0.3, it means they have significant relevance

ISSN: 1479-5876