Fig. 3From: A molecular approach integrating genomic and DNA methylation profiling for tissue of origin identification in lung-specific cancer of unknown primaryDNA methylation patterns from different disease sites and performance of classification models constructed with DNA methylation profiles. A–C Principal component analyses showing pairwise comparison of DNA methylation patterns between tumors from the lung and A cervix, B colon, and C stomach. D–F ROC curves of the TOO classification models based on methylation profiles showing remarkable model performance (AUC > 0.98). AUC: area under curve. ROC: receiver operating characteristic. TOO: tissue of originBack to article page