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Table 2 Cox regression analysis of p-ATF1-T184 and MMP2 in gastric cancer with overall survival

From: Phosphorylated ATF1 at Thr184 promotes metastasis and regulates MMP2 expression in gastric cancer

Characteristics HR CI (95%) P value
Univariate Cox regression analysis   
 P-ATF1-T184 2.399 1.244–4.628 0.009*
 MMP2 1.951 1.026–3.708 0.041*
 P-ATF1-T184 and MMP2 2.624 1.388–4.959 0.003*
 Sex 0.719 0.378–1.367 0.314
 Age 0.682 0.266–1.747 0.426
 Degree of infiltration 24.011 0.271–2.127 × 103 0.165
 Lymph node metastasis 5.018 1.543–16.325 0.007*
 Distant metastasis 5.621 2.623–12.046  < 0.001*
 Tumor size 1.478 0.750–2.914 0.259
 Differentiation 0.617 0.283–1.345 0.225
Multivariate Cox regression analysis   
 P-ATF1-T184 1.712 0.872–3.360 0.118
 Lymph node metastasis 3.671 1.102–12.225 0.034*
 Distant metastasis 3.992 1.843–8.674  < 0.001*
Multivariate Cox regression analysis   
 MMP2 1.691 0.868–3.292 0.122
 Lymph node metastasis 3.875 1.163–12.787 0.027*
 Distant metastasis 4.250 1.955–9.239  < 0.001*
Multivariate Cox regression analysis   
 P-ATF1-T184 and MMP2 2.359 1.227–4.533 0.010*
 Lymph node metastasis 3.640 1.095–12.095 0.035*
 Distant metastasis 4.502 2.066–9.812  < 0.001*