Skip to main content

Table 2 Univariate and multivariate logistic regression analyses of risk variables for association with cognitive impairment

From: The impact of heavy alcohol consumption on cognitive impairment in young old and middle old persons

Variables Univariate
OR (95% CI)
Multivariate
aOR (95% CI)
Alcohol consumption  
 Non-drinkers (Ref = Drinkers) 2.028 (1.616–2.546) 1.531 (0.889–2.635)
 Heavy drinkers 1.512 (0.800–2.859) 0.330 (0.131–0.832)
 Drinkers (Ref = Non-drinkers) 0.493 (0.393–0.619) 0.653 (0.380–1.124)
 Heavy drinker 0.746 (0.387–1.437) 0.216 (0.086–0.542)
Demographic   
 Age, years (Ref = 60–69 y)   
  70+ 2.922 (2.444–3.493) 6.501 (3.076–13.74)
 Gender (Ref = female)   
  Male 1.208 (1.017–1.434) 1.826 (1.334–2.500)
 Race (Ref = Non-Hispanic white)   
  Others 0.975 (0.657–1.446) 1.042 (0.563–1.928)
  Other Hispanic 5.292 (3.641–7.690) 4.352 (2.123–8.922)
  Mexican American 4.485 (3.523–5.709) 3.741 (2.093–6.688)
  Non-Hispanic black 4.708 (3.801–5.831) 5.965 (4.171–8.530)
 Education (Ref = College or above)  
  Under 12th grade 9.069 (7.493–10.97) 5.075 (3.506–7.346)
  High school graduate 2.458 (1.978–3.056) 2.004 (1.501–2.675)
 Marital status (Ref = Married/Living with partner)  
  Widowed/Divorced/Separated 2.019 (1.698–2.400) 1.205 (0.855–1.699)
  Never married 1.641 (1.105–2.438) 1.561 (0.666–3.662)
 Income ratio (Ref = 4–5 (richest))   
  < 1 (Below poverty level) 11.634 (8.362–16.18) 3.077 (1.804–5.251)
  1–1.99 6.107 (4.516–8.260) 2.358 (1.549–3.591)
  2–3.99 2.150 (1.571–2.944) 1.144 (0.720–1.816)
Lifestyle   
 Smoking (Ref = Non-smoker)   
  Current smoker 1.166 (0.908–1.497)  
  Former smoker 1.021 (0.868–1.200)  
 Physical activity (Ref = Active)   
  Inactive 2.208 (1.824–2.671) 1.332 (0.966–1.837)
 BMIb (Ref = Normal)   
  Underweight 1.659 (0.971–2.832)  
  Overweight 0.887 (0.706–1.114)  
  Obese 0.892 (0.718–1.108)  
Attend social events (Ref = No difficulty)  
 Difficulty 3.405 (2.785–4.163) 2.876 (1.810–4.568)
 Comorbidities (Ref = Without)   
  Diabetes Mellitus 1.770 (1.479–2.119) 1.156 (0.734–1.819)
  Hypertension 1.731 (1.473–2.034) 1.554 (1.171–2.063)
  Stroke 2.820 (2.150–3.700) 1.470 (0.752–2.874)
  CKD 2.864 (2.320–3.536) 2.200 (1.455–3.326)
 Interaction term   
  Heavy drinker*Age   8.052 (1.167–55.54)
  Non-drinker*Age   0.486 (0.243–0.972)
  1. Ref: reference; BMI: Body Mass Index; CKD: Chronic Kidney Disease