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Table 2 Primary blood NK and LAK killing of NK-92 cells at 4 h

From: Optimizing NK-92 serial killers: gamma irradiation, CD95/Fas-ligation, and NK or LAK attack limit cytotoxic efficacy

NK activation state Donor # E:T
(PBMC:NK-92)
51Cr 'Target' cells+
Non-irradiated NK-92 10 Gy irradiated NK-92 K562
Unstimulated SC-0394 107:1 7%* 15% 76%
SC-3663 33.5:1 2%* 6%* 23%
SC-6617 60:1 8%* 19% 13%
SC-0975 48:1 7%* 12% 11%
IL-2 LAK SC-0394 23:01 8%* ND 96%
SC-3663 15.2:1 1%* 4%* 47%
SC-6617 55:1 17% 31% 78%
SC-0975 42:1 27% 43% 82%
  1. +%Specific Release. Data are available in Additional file 4: Fig. S2 for the E:T titrations
  2. *Indicates cytotoxicity below the positive killing threshold of 10%