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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Optimizing NK-92 serial killers: gamma irradiation, CD95/Fas-ligation, and NK or LAK attack limit cytotoxic efficacy

Fig. 2

Effects of irradiation on serial killing. NK-92 cells were irradiated on A the day of experiment or B the day before the experiment and cultured with IL-2. Cytotoxicity was measured after 8 h. The slopes of linear regression for B were 40.4 for the non-irradiated cells and 42.5, 37.6, and 27.5 for the 2.5, 5 and 10 Gy irradiated cells, P < 0.001 for 10 Gy. The KFs for the 1:16 E:Ts are indicated in the two boxes in the middle of the figure. E:Ts are graphed on a log10 scale. [***p-value < 0.001 via regression analysis]

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