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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Optimizing NK-92 serial killers: gamma irradiation, CD95/Fas-ligation, and NK or LAK attack limit cytotoxic efficacy

Fig. 1

NK-92 cell cytotoxicity and serial killing frequencies of Raji, Daudi and K562 targets. Each colored line/symbol represents %specific release at a different E:T. Dashed lines represent the expected % dead targets if one target was killed by one effector at an E:T. A Raji cells as ‘targets’. B Daudi cells as ‘targets’. C K562 cells as ‘targets’. The three targets were assayed concurrently. The standard deviations for each data point were less than 2% specific 51Cr release. The cytotoxicity towards Raji cells is significantly greater than Daudi and K562 cells (E:T 1:32 linear regression p < 0.01 & p < 0.001, respectively)

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