Fig. 1

CircZDBF2 is considerably overexpressed in OSCC cells. A CircZDBF2 expression in OSCC cell lines (SCC9, SCC15, SCC25) and HOK cell line was detected by qRT-PCR analysis. B PCR-agarose gel electrophoresis (AGE) was taken to verify the cyclization of circZDBF2. C ZDBF2 mRNA level and circZDBF2 expression in OSCC cells was measured by qRT-PCR upon RNase R treatment. D qRT-PCR was utilized to measure the stability of circZDBF2 and in OSCC cells treated with Act D. E The subcellular location of circZDBF2 in SCC9 and SCC15 cells was identified by FISH assay. ^*P < 0.05, ^**P < 0.01