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Table 3 Correlation of the RHI with soluble biomarkers

From: Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)

 

RHI

r, p value*

n

ME/CFS

ET-1 (pg/ml)

− 0.108, p = 0.716

14

Ang-2 (pg/ml)

− 0.174, p = 0.553

14

ACE activity (U/l)

− 0.083, p = 0.788

13

ACE2 (U/ml)

0.503, p = 0.069

14

IL-8 post-erythrocyte lysis (pg/ml)

− 0.130, p = 0.659

14

PCS

ET-1 (pg/ml)

0.162, p = 0.549

16

Ang-2 (pg/ml)

− 0.165, p = 0.541

16

ACE activity (U/l)

− 0.041, p = 0.882

16

ACE2 (U/ml)

− 0.359, p = 0.173

16

IL-8 post-erythrocyte lysis (pg/ml)

− 0.057, p = 0.833

16

HC

ET-1 (pg/ml)

− 0.179, p = 0.524

15

Ang-2 (pg/ml)

0.125, p = 0.657

15

ACE2 (U/ml)

0.386, p = 0.157

15

  1. *For statistical analysis, the Spearman correlation was performed
  2. ACE Angiotensin-converting enzyme, Ang-2Angiopoietin-2; ET-1 Endothelin-1, HC healthy control; RHI reactive hyperaemia index