Table 5 Univariate analysis
Parameters | Hazard ratio | DFS | Hazard ratio | OS | ||
|---|---|---|---|---|---|---|
95% CI | P-value | 95% CI | P-value | |||
TNM stage (I + IIVS.III) | 1.65 | (1.51, 2.16) | 0.678 | 1.81 | (1.32–2.45) | 0.505 |
Lymph node invasion (yes vs no) | 2.46 | (1.29, 4.78) | < 0.001 | 2.86 | (1.84–5.13) | < 0.001 |
Microvascular invasion (yes vs no) | 1.87 | (1.31–1.96) | 0.728 | 1.63 | (1.35–1.88) | 0.285 |
HBV (yes vs no) | 2.13 | (1.45–4.23) | < 0.001 | 1.91 | (1.63–4.15) | < 0.001 |
Child–Pugh grade (A vs. B) | 1.84 | (1.47–1.91) | 0.123 | 1.21 | (0.99–1.64) | 0.415 |
CD68 (high VS low) | 2.95 | (1.87–4.65) | < 0.001 | 3.08 | (1.95–4.87) | < 0.001 |
SIRPα (high VS low) | 3.06 | (1.86–5.02) | < 0.001 | 3.23 | (1.96–5.35) | < 0.001 |
PD1 (high VS low) | 2.39 | (1.52–3.78) | < 0.001 | 2.36 | (1.50–3.72) | < 0.001 |
CD68/SIRPα (double high VS others) | 2.38 | (0.77–7.36) | 0.0251 | 5.05 | (1.46–17.45) | 0.0203 |
CD68/PD1 (double high VS others) | 2.02 | (1.04–3.94) | 0.0682 | 2.12 | (1.08–4.15) | 0.0495 |