Base line characteristics | All | non-DKD | DKD | P value |
---|---|---|---|---|
Patient population, n | 816 | 408 | 408 | Â |
Male, n (%) | 541 (66.3) | 291 (71.3) | 250 (61.3) | 0.002 |
Age (years) | 56.00 (48.25–65.00) | 52.5 (47, 60) | 61 (50, 71) | 0.000 |
BMI (kg/m2) | 26.03 (24.22, 28.61) | 25.79 (24.46, 28.24) | 26.30 (23.96, 29.06) | 0.343 |
Hypertension (%) | 349 (42.8) | 157 (38.5) | 192 (47.1) | 0.013 |
Cardiovascular disease (%) | 194 (23.8) | 79 (19.4) | 115 (28.2) | 0.292 |
Cerebrovascular disease (%) | 81 (9.9) | 36 (8.8) | 45 (11) | 0.003 |
Peripheral neuropathy (%) | 31 (3.8) | 13 (3.2) | 18 (4.4) | 0.360 |
Diabetic retinopathy (%) | 21 (2.6) | 9 (2.2) | 12 (2.9) | 0.507 |
eGFR CKD-EPI (ml/min/1.73m2) | 98.42 ± 18.63 | 103.25 ± 16.15 | 93.6 ± 19.69 | 0.000 |
SCR (μmol/L) | 68.62 ± 14.06 | 67.13 ± 12.85 | 70.1 ± 15.05 | 0.003 |
BUN (mmol/L) | 5.36 (4.5, 6.43) | 5.22 (4.47, 6.16) | 5.51 (4.53, 6.66) | 0.004 |
SUA (μmol/L) | 331.50 ± 91.85 | 336 ± 84.46 | 326.99 ± 98.58 | 0.161 |
HbA1c (%) | 6.8 (6.3, 77.7) | 6.6 (6.18, 7.30) | 7.00 (6.41, 8.03) | 0.000 |
ALB (g/L) | 43.21 ± 4.04 | 43.89 ± 3.63 | 42.54 ± 4.31 | 0.000 |
TC (mmol/L) | 4.41 (3.72, 5.23) | 4.46 (3.85, 5.24) | 4.33 (3.65, 5.23) | 0.153 |
TG (mmol/L) | 1.58 (1.11, 2.35) | 1.69 (1.16, 2.42) | 1.50 (1.03, 2.21) | 0.019 |
HDL (mmol/L) | 1.04 (0.89, 1.28) | 1.03 (0.88, 1.26) | 1.07 (0.90, 1.31) | 0.107 |
LDL (mmol/L) | 2.76 ± 0.91 | 2.82 ± 0.86 | 2.71 ± 0.95 | 0.09 |
K (mmol/L) | 4.09 ± 0.38 | 4.07 ± 0.33 | 4.1 ± 0.42 | 0.372 |
Na (mmol/L) | 142 (140, 143.3) | 142.00 (140.80, 143.88) | 141.60 (139.4, 143.00) | 0.000 |
Ca (mmol/L) | 2.29 ± 0.11 | 2.29 ± 0.10 | 2.28 ± 0.12 | 0.381 |
P (mmol/L) | 1.18 ± 0.18 | 1.20 ± 0.18 | 1.17 ± 0.18 | 0.023 |
Bicarbonate (mmol/L) | 26.13 (24.95, 27.5) | 25.98 (24.9, 27.10) | 26.23 (25.01, 27.78) | 0.017 |
Hcy | 12.59 (10.17, 15.45) | 1175 (9.71, 14.16) | 13.61 (10.74, 16.65) | 0.000 |
Hb (g/L) | 141.93 ± 18.8 | 145.51 ± 16.82 | 138.34 ± 19.98 | 0.000 |
NLR | 1.84 (1.42, 2.44) | 1.76 (1.35, 2.32) | 1.97 (1.45, 2.61) | 0.000 |
FIB (g/L) | 3.09 (2.70, 3.54) | 3.00 (2.65, 3.42) | 3.18 (2.77, 3.69) | 0.000 |