New challenges for microRNAs in acute pancreatitis: progress and treatment

Table 3 Summary of studies of the miRNA molecular markers related to the early diagnosis, prognosis and evaluation of the severity of AP

Molecular marker	Expression	Patient	Clinical relevance	References
miR-92b, miR-10a, miR-7	Up	AP	Diagnosis	[67]
miR-551-5p, miR-126a-5p	Up	AP	Severity assessment	[67, 70]
miR-24-3p, miR-222-3p, miR-361-5p and miR-1246	Up	HTAP	Severity assessment	[71]
miR-181a-5p	Down	HTAP	Severity assessment	[71]
miR-22-3p, 1260b, miR-762, miR-23b and miR-23a	Up	AP with ALI	Diagnosis, prognosis	[72]
miR-550a*, miR-324-5p, miR-484, miR-331-3p, miR-22-3p, miR-140-3p and miR-342-3p	Down	AP with ALI	Diagnosis, prognosis	[72]
miR-146a, miR-146b	Up	AP	Prognosis	[73]
miR-192-5p	Down	AP with NAFLD	Diagnosis	[74]
miR-372	Up	HTGAP	Diagnosis, prognosis	[75]
miR-29a	Up	AP	Severity assessment, prognosis	[76]
miR-7, miR-9, miR-122 and miR-141	Up	AP	Diagnosis, prognosis	[77]
miR-155, miR-21	Down	AP	Diagnosis, severity assessment, prognosis	[78]
miR-127	Down	AP with ALI	Diagnosis, severity assessment, prognosis	[79]
miR-216	Up	AP	Diagnosis, severity assessment	[80]

ISSN: 1479-5876