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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Computer-assisted three-dimensional quantitation of programmed death-ligand 1 in non-small cell lung cancer using tissue clearing technology

Fig. 5

Specimen after 3D imaging could be recovered for standard pathology examinations for non-small cell lung cancer. Comparing the pre-processing (A) and post-processing (B) tissue, the standard H&E staining performed on 4 μm sections showed similar morphological details. The pre-processing (C) and post-processing (D) tissue also showed comparable TTF-1 staining by immunohistochemistry. The EGFR mutation analysis performed using pre- and post-processing tissue yielded identical results in all the tested cases (n = 3) (E) (Scale bar: 40 μm)

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