Fig. 4

The level of pRNFL, pVD and VFMS in 8 peripapillary regions among four groups. The regional level of the peripapillary retinal nerve fibre layer (pRNFL), peripapillary vessel density (pVD) and visual filed mean sensitivity (VFMS) were showed separately in A–C. A The TS and TI regional pRNFL in Group 3 and 4 were statistically significant thicker than that in Group1. However, in IT and IN region, the pRNFL in Group 4 was thinner than that in Group 3 and Group1, separately. B The regional pVD decreased along with the refractive error diopters increased. This decline was particularly pronounced in Group 4. C The regional VFMS decreased significantly in Group 4 in all the 8 peripapillary areas. * P < 0.05, ** P < 0.01, ***P < 0.001(comparison in each sector between four groups). a, b, c: statistical differences between groups were marked by letters, with groups sharing at least one similar letter presenting no statistically significant difference (p ≥ 0.05) and groups with all different letters presenting a significant difference (p < 0.05). TS: temporal superior; TI: temporal inferior; ST: superior temporal; IT: inferior temporal; SN: superior nasal; IN: inferior nasal; NS: nasal superior; NI: nasal inferior