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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

Fig. 3

Dysregulated metabolites in patients with sepsis. A Orthogonal partial least-squares discriminant analysis (OPLS-DA) of serum metabolism showing that patients with sepsis substantially differed from normal controls (NCs) in both positive (left) and negative ion modes (right). B The top 30 metabolites with high discriminatory accuracy ranked by variable importance in projection (VIP) score in positive ion mode (left) and negative ion mode (right). C The area under the receiver operating characteristic curve (AUROC) to assess the discriminatory accuracy of 51 metabolites (left) and 25 metabolites (right) in differentiating patients with sepsis from normal controls in the derivation and validation groups

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