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Table 3 Performance of the 90-gene expression assay in clinicopathological subsets

From: Clinical validation of a 90-gene expression test for tumor tissue of origin diagnosis: a large-scale multicenter study of 1417 patients

Clinical variables

Number

Agreement

Accuracy (%)

Study

   

 Retrospective

924

884

95.7

 Prospective

493

454

92.1

Histologic grade

   

 Well-moderately differentiated

418

399

95.5

 Poorly differentiated/Undifferentiated

694

656

94.5

Histological type

   

 Adenocarcinoma

943

898

95.2

 Squamous cell carcinoma

166

151

91.0

 Urothelial carcinoma

55

53

95.4

 Melanoma

54

48

88.9

 Neuroendocrine tumor

52

49

94.2

 Tumor

49

45

91.8

  Sarcoma

46

43

93.5

  Germ cell tumor

40

39

97.5

  Mesothelioma

12

12

100

Institution

   

 BCH

518

489

94.4

 FUSCC

424

403

95.0

 ZCH

475

446

93.9