Fig. 1

NAMPT expression is associated with BRAF mutations in TCGA cohort. A Cumulative distribution function (cdf) plot of NAMPT expression in BRAF wild-type (WT, in cyan) and BRAF mutated (MUT, in red) tumor samples from the TCGA cohort. The shift toward the right for the cdf indicates NAMPT increased expression in BRAF mutated samples. N of samples for each group are indicated in the brackets. Statistical significance was calculated using Kolmogorov–Smirnoff test. B Boxplots representing NAMPT expression levels in BRAF WT vs. BRAF MUT SKCM and THCA samples of the TCGA cohort. N of samples in each group are indicated (excluding from the analysis NRAS and C-KIT mutated samples). Statistical significance was calculated using Mann–Whitney test. Significance was represented as: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001