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Table 4 Prospective analysis of associations between STB levels and hypertension incidence

From: The association between bilirubin and hypertension among a Chinese ageing cohort: a prospective follow-up study

 

STB quartiles

1

 < 9.3 μmol/L

2

9.3 ~ 11.8 μmol/L

3

11.9 ~ 15.2 μmol/L

4

 > 15.3 μmol/L

P for trend

Crude Model

Reference

1.14 (0.85–1.52)

1.40 (1.05–1.85)

1.49 (1.13–1.97)

0.017

Model 1

Reference

1.10 (0.82–1.47)

1.49 (1.12–1.97)

1.68 (1.27–2.22)

 < 0.001

Model 2

Reference

1.11 (0.83–1.48)

1.50 (1.13–1.99)

1.68 (1.27–2.23)

 < 0.001

Model 3

Reference

1.21 (0.90–1.63)

1.60 (1.20–2.12)

1.76 (1.32–2.34)

 < 0.001

Model 4

Reference

1.19 (0.89–1.60)

1.46 (1.10–1.94)

1.68 (1.26–2.23)

0.002

  1. Multivariable-adjusted Cox regression models were used to assess the hypertension incidence risk by STB quartiles. Crude model: Only included STB level at the baseline. Multivariable model 1: Included variables of age, gender, BMI, and WC on the basis of the Crude model. Multivariable model 2: Further included variables of SBP, DBP, and DM at baseline on the basis of the Multivariable model 1. Multivariable model 3: Further included variables of FPGlog10, AST, and SCrSQRT on the basis of the Multivariable model 2. Multivariable model 4: Further included the variable of smoking status on the basis of the Multivariable model 3
  2. STB, serum total bilirubin; BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; T2DM, type 2 diabetes mellitus; AST, aspartate aminotransferase; FPG, fasting plasma glucose; SCr, serum creatinine