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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Mini-XT, a miniaturized tagmentation-based protocol for efficient sequencing of SARS-CoV-2

Fig. 3

Sequencing results from Mini-XT and Illumina DNA Flex library preparation are comparable. A The percentage coverage was very similar between each of 333 samples prepared by both library preparation protocols. B A subset of the consensus sequences (named according to protocol and sample number) were placed in a phylogenetic tree with branch lengths shown in nucleotide substitutions per site and the lineages comprising the main branches indicated. The same samples sequenced using both protocols cluster together on the tree. C The same SNVs were identified in each sample by both platforms. This is illustrated in a SnipIt plot of 15 pairs of sequences representing each branch of the tree and aligned to a reference Wuhan sequence modified to contain all invariant SNVs identified in these samples

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