Fig. 1

GC cells induce malignant progression of GES-1 cells via exosomes. A GES-1 cells were co-cultured with AGS cells. B GES-1 cell migratory before and after being co-cultured with AGS cells was detected by wound healing assay. C Transwell assay was performed to detect the invasive capability of GES-1 cell before and after being co-cultured with AGS cells. D Wound healing assay was performed to measure the migration of AGS-cultured GES-1 cells before and after treatment with GW4869. E Transwell assay was taken to determine AGS-cultured GES-1 cell invasion before and after treatment with GW4869. ^**P < 0.01