Fig. 2

Construction and evaluation of the immunoscore (IS) model. A Summary of inferred immune cell subset proportions in the TCGA cohort; B Least absolute shrinkage and selection operator (LASSO) coefficient profiles of the 22 immunocytes fractions; C Twentyfold cross-validation for tuning parameter selection in the LASSO model; D Time-dependent receiver-operating characteristics (ROC) curves for overall survival prediction by the IS model in the TCGA cohort; E–G Kaplan–Meier curves for overall survival prediction by the IS model in the TCGA cohort, GSE62254 cohort and GSE15459 cohort, respectively; H The fraction of tumor microenvironment immune cells in high- and low-IS groups in the GSE62254 cohort