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Table 2 Participant Quality of Life, disability scores and serology

From: Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients

  HC ME/CFS P-value
SF-36 (%)    
 Physical functioning 94.0 ± 17.29 37.5 ± 30.93  < 0.0001
 Physical role 95.0 ± 11.71 24.38 ± 19.19  < 0.0001
 Pain 90.25 ± 20.83 40.0 ± 27.99 0.003
 General Health 78.75 ± 11.69 29.59 ± 18.37  < 0.0001
 Social functioning 98.75 ± 3.95 27.5 ± 26.22  < 0.0001
 Emotional role 99.17 ± 2.63 69.99 ± 23.31 0.002
 Emotional wellbeing 76.96 ± 11.04 39.17 ± 12.23  < 0.0001
WHO DAS (%)    
 Communication & understanding 1.62 ± 2.09 45.83 ± 24.29  < 0.0001
 Mobility 2.50 ± 6.35 56.0 ± 30.26  < 0.0001
 Self-care 0.0 ± 0.0 33.13 ± 29.47  < 0.0001
 Interpersonal relationships 1.25 ± 10.62 33.13 ± 31.6 0.009
 Life activities 6.25 ± 10.62 66.87 ± 24.66  < 0.0001
 Participation in Society 2.19 ± 3.62 57.49 ± 23.11  < 0.0001
Full blood count    
 White Cell Count (× 109/L) 5.97 ± 0.79 5.58 ± 0.84 0.247
 Lymphocytes (× 109/L) 2.02 ± 0.69 1.60 ± 0.42 0.315
 Neutrophils (× 109/L) 3.37 ± 0.69 3.29 ± 0.86 0.684
 Monocytes (× 109/L) 0.44 ± 0.10 0.41 ± 0.07 0.436
 Eosinophils (× 109/L) 0.14 ± 0.11 0.16 ± 0.09 0.579
 Basophils (× 109/L) 0.03 ± 0.01 0.04 ± 0.01 0.075
 Platelets (× 109/L) 250.40 ± 55.41 255.4 ± 31.49 0.684
 Red Cell Count (× 1012/L) 4.47 ± 0.45 4.47 ± 0.34 0.912
 Haematocrit 0.41 ± 0.04 0.41 ± 0.03 0.631
 Haemoglobin (g/L) 134.40 ± 16.34 135.4 ± 11.71 0.853
  1. Values in bold are statistically significant
  2. HC healthy controls, ME Myalgic encephalomyelitis, CFS chronic fatigue syndrome, SF-36 36-item short form survey, WHO world health organization, DAS disability assessment schedule