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Table 2 Participant Quality of Life, disability scores and serology

From: Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients

 

HC

ME/CFS

P-value

SF-36 (%)

   

 Physical functioning

94.0 ± 17.29

37.5 ± 30.93

 < 0.0001

 Physical role

95.0 ± 11.71

24.38 ± 19.19

 < 0.0001

 Pain

90.25 ± 20.83

40.0 ± 27.99

0.003

 General Health

78.75 ± 11.69

29.59 ± 18.37

 < 0.0001

 Social functioning

98.75 ± 3.95

27.5 ± 26.22

 < 0.0001

 Emotional role

99.17 ± 2.63

69.99 ± 23.31

0.002

 Emotional wellbeing

76.96 ± 11.04

39.17 ± 12.23

 < 0.0001

WHO DAS (%)

   

 Communication & understanding

1.62 ± 2.09

45.83 ± 24.29

 < 0.0001

 Mobility

2.50 ± 6.35

56.0 ± 30.26

 < 0.0001

 Self-care

0.0 ± 0.0

33.13 ± 29.47

 < 0.0001

 Interpersonal relationships

1.25 ± 10.62

33.13 ± 31.6

0.009

 Life activities

6.25 ± 10.62

66.87 ± 24.66

 < 0.0001

 Participation in Society

2.19 ± 3.62

57.49 ± 23.11

 < 0.0001

Full blood count

   

 White Cell Count (× 109/L)

5.97 ± 0.79

5.58 ± 0.84

0.247

 Lymphocytes (× 109/L)

2.02 ± 0.69

1.60 ± 0.42

0.315

 Neutrophils (× 109/L)

3.37 ± 0.69

3.29 ± 0.86

0.684

 Monocytes (× 109/L)

0.44 ± 0.10

0.41 ± 0.07

0.436

 Eosinophils (× 109/L)

0.14 ± 0.11

0.16 ± 0.09

0.579

 Basophils (× 109/L)

0.03 ± 0.01

0.04 ± 0.01

0.075

 Platelets (× 109/L)

250.40 ± 55.41

255.4 ± 31.49

0.684

 Red Cell Count (× 1012/L)

4.47 ± 0.45

4.47 ± 0.34

0.912

 Haematocrit

0.41 ± 0.04

0.41 ± 0.03

0.631

 Haemoglobin (g/L)

134.40 ± 16.34

135.4 ± 11.71

0.853

  1. Values in bold are statistically significant
  2. HC healthy controls, ME Myalgic encephalomyelitis, CFS chronic fatigue syndrome, SF-36 36-item short form survey, WHO world health organization, DAS disability assessment schedule